Human HPGD/PGDH1/SDR36C1 (His tag) recombinant protein

Cat.#: 518533

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Product Information

  • Product Name
    Human HPGD/PGDH1/SDR36C1 (His tag) recombinant protein
  • Documents
  • Description
    15-hydroxyprostaglandin dehydrogenase [NAD(+)], also known as Prostaglandin dehydrogenase 1, 15-PGDH, HPGD and PGDH1, belongs to the short-chain dehydrogenases/reductases (SDR) family. HPGD localizes to the cytoplasm and can be found in colon epithelium, existing as a homodimer. HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. HPGD is down-regulated by cortisol, dexamethasone and betamethasone, up-regulated by TGFB1. HPGD inhibits in vivo proliferation of colon cancer cells. HPGD is the key enzyme for the inactivation of prostaglandins, and thus regulates processes such as inflammation or proliferation.
  • Protein name
    hydroxyprostaglandin dehydrogenase 15-(NAD)(HPGD)
  • Protein short names
    PGDH1; SDR36C1
  • Uniprot ID
    P15428
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human HPGD/PGDH1/SDR36C1 Met1-Gln266 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human HPGD/PGDH1/SDR36C1 (His tag) recombinant protein

    Human HPGD/PGDH1/SDR36C1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"