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  • Human HPGD/15-PGDH (His Tag) recombinant protein

Human HPGD/15-PGDH (His Tag) recombinant protein

Cat.#: 501737

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Product Information

  • Product Name
    Human HPGD/15-PGDH (His Tag) recombinant protein
  • Documents
  • Description
    Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
  • Protein name
    15-hydroxyprostaglandin dehydrogenase [NAD(+)]
  • Protein short names
    PGDH1; PHOAR1; PGDH; AV026552; MGC14001; HPGD; 15-PGDH; SDR36C1
  • Uniprot ID
    P15428
  • Gene Name
    HPGD; PGDH1; SDR36C1
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human HPGD (NP_000851.2) (Met 1-Gln 266) was expressed, with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human HPGD comprises 272 amino acids and has a predicted molecular mass of 29.7 kDa. It migrates as an approximately 27 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Activity
    Measure by the production of NADH during the oxidation of PGF2α. The specific activity is >1,500 pmoles/min/μg.
  • Validations

    Human HPGD / 15-PGDH Protein (His Tag) SDS-PAGE

    Human HPGD / 15-PGDH Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"