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Product Name
Human HMBS/PBGD/UPS (His tag) recombinant protein
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Description
Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.
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Protein name
hydroxymethylbilane synthase(HMBS)
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Protein short names
PBGD; UPS
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Uniprot ID
P08397
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human HMBS/PBGD/UPS Ser2-His361 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human HMBS/PBGD/UPS (His tag) recombinant protein
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