Human HAVCR2/TIM3/TIMD3 (His tag) recombinant protein

Cat.#: 519309

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Product Information

  • Product Name
    Human HAVCR2/TIM3/TIMD3 (His tag) recombinant protein
  • Documents
  • Description
    T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21), an extracellular region (aa 22-202) with one Ig-like V-type domain, a transmembrane segment (aa 203-223), and a cytoplasmic domain (aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
  • Protein name
    hepatitis A virus cellular receptor 2(HAVCR2)
  • Protein short names
    TIM3; TIMD3
  • Uniprot ID
    Q8TDQ0
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human HAVCR2/TIM3/TIMD3 Ser22-Arg200 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human HAVCR2/TIM3/TIMD3 (His tag) recombinant protein

    Human HAVCR2/TIM3/TIMD3 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"