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Product Name
Human HAVCR2/TIM3/TIMD3 (His tag) recombinant protein
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Description
T-Cell Membrane Protein 3 (TIM3) is a single-pass type I membrane protein that belongs to the TIM family of immunoglobulin superfamily. TIM3 includes a signal sequence (aa 1-21), an extracellular region (aa 22-202) with one Ig-like V-type domain, a transmembrane segment (aa 203-223), and a cytoplasmic domain (aa 224 - 301). TIM3 regulates macrophage activation, inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. It may be also involved in T-cell homing and as a receptor for LGALS9.
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Protein name
hepatitis A virus cellular receptor 2(HAVCR2)
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Protein short names
TIM3; TIMD3
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Uniprot ID
Q8TDQ0
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human HAVCR2/TIM3/TIMD3 Ser22-Arg200 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human HAVCR2/TIM3/TIMD3 (His tag) recombinant protein
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