Human GOLM1/GP73 (His Tag) recombinant protein

Human GOLM1/GP73 (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Golgi membrane protein 1, also known as Golgi membrane protein GP73, Golgi phosphoprotein 2 and GOLM1, is a protein which belongs to the GOLM1 / CASC4 family. GOLM1 is widely expressed. It is highly expressed in colon, prostate, trachea and stomach. It is expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. It is predominantly expressed by cells of the epithelial lineage. GOLM1 is expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression of GOLM1 does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), GOLM1 is strongly expressed in hepatocyte-derived syncitial giant cells. GOLM1 is constitutively expressed by biliary epithelial cells but not by hepatocytes.

Golgi membrane protein 1

AW125446; FLJ23608; RP11-379P1.3; FLJ22634; C9ORF155; GOLM1; D030064E01RIK; PSEC0257; GP73; MGC107447; BA379P1.3; HEL46; GOLPH2; 2310001L02RIK

Q8NBJ4

GOLM1; C9orf155; GOLPH2; PSEC0242; UNQ686/PRO1326

Human Cells

A DNA sequence encoding the human GOLM1 isoform 1 (Q8NBJ4-1) (Val 40-Leu 401) was fused with a polyhistidine tag at the C-terminus and a Met at the N-terminus.

Human

The recombinant human GOLM1 consists of 374 amino acids and has a predicted molecular mass of 42.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh GOLM1 is approximately 60 kDa.

> 90 % as determined by SDS-PAGE