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Product Name
Human GMFB (His tag) recombinant protein
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Description
Glia maturation factor beta (GMFB) contains a ADF-H domain，which is a member of the actin-binding proteins ADF family, GMF subfamily. It is a nerve growth factor implicated in nervous system development, angiogenesis and immune function. GMFB causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells. It is phosphorylated after phorbol ester stimulation, and is crucial for the nervous system. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
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Protein name
glia maturation factor beta(GMFB)
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Uniprot ID
P60983
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human GMFB Met1-His142 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human GMFB (His tag) recombinant protein
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