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Product Name
Anti-GMFB antibody
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Description
Rabbit Polyclonal to Human GMFB
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Tested applications
WB, ICC/IF, IF
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Species reactivity
Human GMFB
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Alternative names
3110001H22Rik antibody; 3110001O16Rik antibody; AI851627 antibody; C79176 antibody; D14Ertd630e antibody; glia maturation factor beta antibody; glia maturation factor beta antibody; GMF antibody; GMF-beta antibody; GMF-beta antibody; GMF antibody; C79176 antibody; AI851627 antibody; D14Ertd630e antibody; 3110001H22Rik antibody; 3110001O16Rik antibody
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human GMFB, and purified by antigen affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
WB: 5-10 μg/ml
ICC/IF: 0.5-3 μg/mL
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Validations
GMFB Antibody, Rabbit PAb, Antigen Affinity Purified, Western blot
GMFB Antibody, Rabbit PAb, Antigen Affinity Purified, Immunofluorescence
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Background
GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis and immune function. It is especially crucial for the nervous system. GMFB causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. It contains 1 ADF-H domain and is phosphorylated after phorbol ester stimulation. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"