• Human GLB1/ELNR1 (His tag) recombinant protein

Human GLB1/ELNR1 (His tag) recombinant protein

Cat.#: 518103

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Product Information

  • Product Name
    Human GLB1/ELNR1 (His tag) recombinant protein
  • Documents
  • Description
    β Galactosidase is a lysosomal β Galactosidase that hydrolyzes the terminal β Galactose from Ganglioside and Keratan sulfate. In lysosome, the mature β Galactosidase protein associates with Cathepsin A and Neuraminidase 1 to form the lysosomal multienzyme complex . An alternative splicing at the RNA level of β Galactosidase results a catalytically inactive β Galactosidase that plays an important role in vascular development. Defects of β-galactosidase (GLB1) are the cause of diseases like GM1-gangliosidosis which is a lysosomal storage disease and Morquio Syndrome B that cause patients to have abnormal elastic fibers. More than 100 mutations have been identified for β Galactosidase, which result in different residual activities of the mutant enzymes and a spectrum of symptoms in the two related diseases.
  • Protein name
    galactosidase beta 1(GLB1)
  • Protein short names
    ELNR1
  • Uniprot ID
    P16278
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human GLB1/ELNR1 Leu24-Val677 is expressed with a 6His tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human GLB1/ELNR1 (His tag) recombinant protein

    Human GLB1/ELNR1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"