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Product Name
Anti-GLB1/Beta-galactosidase Rabbit antibody
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Description
GLB1/Beta-galactosidase Rabbit polyclonal antibody
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Tested applications
WB, FC
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Species reactivity
Human, Mouse, Rat
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Alternative names
EBP; ELNR1; MPS4B antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human GLB1
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Clonality
Polyclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at -20°C. Stable for 12 months from date of receipt.
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Applications
WB: 1/2000-1/10000
FC: 1/20
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Validations
Western blot detection of GLB1 in K562,C6,3T3,Hela cell lysates using GLB1 Rabbit pAb(1:1000 diluted).Predicted band size:76kDa.Observed band size:80kDa.
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Background
Swiss-Prot Acc.P16278.Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.Isoform 2 has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"