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Product Name
Human FIS1/TTC11/CGI-135 (His tag) recombinant protein
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Description
Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
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Protein name
fission, mitochondrial 1(FIS1)
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Protein short names
TTC11; CGI-135
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Uniprot ID
Q9Y3D6
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human FIS1/TTC11/CGI-135 Met1-Gly122 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human FIS1/TTC11/CGI-135 (His tag) recombinant protein
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