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Product Name
Anti-TTC11/FIS1 Rabbit antibody
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Description
TTC11/FIS1 Rabbit monoclonal antibody
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Tested applications
WB, IHC-P, ICC/IF
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Species reactivity
Human
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Alternative names
TTC11; CGI-135 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human TTC11
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Clonality
Monoclonal
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Formulation
50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
WB: 1/1000-1/5000
IHC: 1/20
ICC/IF: 1/20
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Validations
Western blot detection of TTC11/FIS1 in Jurkat,Hela cell lysates using TTC11/FIS1 Rabbit mAb(1:1000 diluted).Predicted band size:17kDa.Observed band size:17kDa.
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Background
Swiss-Prot Acc.Q9Y3D6.Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"