Human ESR2/ESTRB/NR3A2 (His tag) recombinant protein

Cat.#: 518212

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Product Information

  • Product Name
    Human ESR2/ESTRB/NR3A2 (His tag) recombinant protein
  • Documents
  • Description
    Estrogen Receptor Beta (ESR2) is a nuclear protein that belongs to the nuclear hormone receptor family of NR3 subfamily. It contains one nuclear receptor DNA-binding domain and is expressed in many tissues at a lower level. ESR2 is a nuclear hormone receptor. It binds estrogens with an affinity similar to that of ESR1 and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
  • Protein name
    estrogen receptor 2(ESR2)
  • Protein short names
    ESTRB; NR3A2
  • Uniprot ID
    Q92731-3
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human ESR2/ESTRB/NR3A2 Met1-Ala323 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human ESR2/ESTRB/NR3A2 (His tag) recombinant protein

    Human ESR2/ESTRB/NR3A2 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"