Human EPHA7/EHK3/HEK11 (His tag) recombinant protein

Human EPHA7/EHK3/HEK11 (His tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Ephrin Type-A Receptor 7 (EPHA7) is a single-pass type I membrane protein which belongs to the Eph family of transmembrane receptor tyrosine kinases. It contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile alpha motif) domain. EPHA7 is a receptor for members of the ephrin-A family. Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. EPHA7 functions as a repulsive guidance molecule during the targeting of retinal axons to the superior colliculus and of neocortical axons to the thalamus. EPHA7 is expressed at a substantial level in most human lung cancers. The high expression of EPHA7 protein may participate in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma. EPHA7 may involve in smoking related lung carcinogenesis.

EPH receptor A7(EPHA7)

EHK3; HEK11

Q15375

Human Cells

A DNA sequence encoding the Human EPHA7/EHK3/HEK11 Gln28-Ile556 is expressed with a 6His tag at the C-terminus.

Human

>95% as determined by SDS-PAGE.