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Product Name
Human EFNA1/EPLG1/LERK1/TNFAIP4 (Fc tag) recombinant protein
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Description
Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can be down-regulated in primary glioma tissues compared to the normal tissues. The soluble monomeric form is expressed in the glioblastoma multiforme (GBM) and breast cancer cells. Soluble Ephrin-A1 is necessary for the transformation of HeLa and SK-BR3 cells and participates in the relocalization of EPHA2 away from sites of cell-cell contact during transformation. Ephrin-A1 plays an important role in angiogenesis and tumor neovascularization.
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Protein name
ephrin A1(EFNA1)
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Protein short names
EPLG1; LERK1; TNFAIP4
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Uniprot ID
P20827
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human EFNA1/EPLG1/LERK1/TNFAIP4 Asp19-Ser182 is expressed with a Fc tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human EFNA1/EPLG1/LERK1/TNFAIP4 (Fc tag) recombinant protein
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