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Human Cystatin E / CST6 (His Tag) recombinant protein

Cat.#: 501335

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Product Information

  • Product Name
    Human Cystatin E / CST6 (His Tag) recombinant protein
  • Documents
  • Description
    Shows moderate inhibition of cathepsin B but is not active against cathepsin C.
  • Protein name
    Cystatin-M
  • Uniprot ID
    Q15828
  • Gene Name
    CST6
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human cystatin E/M protein (NP_001314.1) (Met 1-Met 149) was expressed with a C-terminal polyhistidine-tag.
  • Protein Species
    Human
  • Molecular weight
    The mature form of recombinant human cystatin E/M consists of 132 amino acids and predicts a molecular mass of 15 kDa. It exists as two major forms with an identical N-terminal sequence. As a result of glycosylation, rh cystatin E/M migrates as doublets with the molecular mass of approximately 15 and 21 kDa respectively in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate ZF RAMC, R&D Systems, Catalog # ES009. IC50<2nM.
  • Validations

    Human Cystatin E / CST6 Protein (His Tag) SDS-PAGE

    Human Cystatin E / CST6 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"