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Product Name
Human CTHRC1/UNQ762/PRO1550 (His tag) recombinant protein
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Description
Collagen triple helix repeat-containing protein 1 is a protein that in humans is encoded by the CTHRC1 gene. It acts as a negative regulator of collagen matrix deposition. It may cause the disease of Barrett esophagus . Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes.
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Protein name
collagen triple helix repeat containing 1(CTHRC1)
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Protein short names
UNQ762; PRO1550
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Uniprot ID
Q96CG8
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CTHRC1/UNQ762/PRO1550 Ser31-Lys243 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CTHRC1/UNQ762/PRO1550 (His tag) recombinant protein
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