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Product Name
Human CSF2RA/CSF2R/CSF2RY (His tag) recombinant protein
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Description
Granulocyte-Macrophage Colony-Stimulating Factor Receptor Subunit α (CSF2RA) is a single-pass type I membrane protein which belongs to the type I cytokine receptor family of Type 5 subfamily. The CSF2RA gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes with some of the isoforms being membrane-bound and others being soluble. CSF2RA is a low affinity receptor for granulocyte-macrophage colony-stimulating factor. CSF2RA transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Defects in CSF2RA are the cause of pulmonary surfactant metabolism dysfunction type 4 (SMDP4).
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Protein name
colony stimulating factor 2 receptor alpha subunit(CSF2RA)
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Protein short names
CSF2R; CSF2RY
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Uniprot ID
P15509
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human CSF2RA/CSF2R/CSF2RY Glu23-Gly320 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human CSF2RA/CSF2R/CSF2RY (His tag) recombinant protein
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