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Human CD116/GM-CSFR (His Tag) recombinant protein

Cat.#: 502602

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Product Information

  • Product Name
    Human CD116/GM-CSFR (His Tag) recombinant protein
  • Documents
  • Description
    Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.
  • Protein name
    Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
  • Protein short names
    GMCSFR; GM-CSFR; GMR; CSF2RY; SMDP4; CDW116; CSF2RX; CSF2RAY; CSF2R; CSF2RAX; GM-CSF-RA; CSFGMRA; GM-CSF-R-ALPHA; CSF2RA; CD116
  • Uniprot ID
    P15509
  • Gene Name
    CSF2RA; CSF2R; CSF2RY
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the extracellular domain (Met 1-Gly 320) of human GM-CSFR? (P15509-1) was expressed with the C-terminal fused polyhistidine tag.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human GM-CSFR? consists of 309 amino acids and has a predicted molecular mass of 36 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh GM-CSFR? is approximately 60-65 kDa due to glycosylation.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    Measured by its ability to inhibit GM-CSF dependent proliferation of TF-1 human erythroleukemic cells. The ED50 for this effect is typically 3-5 μg/ml.
  • Validations

    Human CSF2RA / GM-CSFR / CD116 Protein (His Tag) SDS-PAGE

    Human CSF2RA / GM-CSFR / CD116 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"