Human CRADD/RAIDD recombinant protein

Cat.#: 518134

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Product Information

  • Product Name
    Human CRADD/RAIDD recombinant protein
  • Documents
  • Description
    Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
  • Protein name
    CASP2 and RIPK1 domain containing adaptor with death domain(CRADD)
  • Protein short names
    RAIDD
  • Uniprot ID
    P78560
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human CRADD/RAIDD Met1-Glu199 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human CRADD/RAIDD recombinant protein

    Human CRADD/RAIDD recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"