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Product Name
Anti-RAIDD Rabbit antibody
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Description
RAIDD Rabbit monoclonal antibody
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Tested applications
WB, ICC/IF, FC, IP
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Species reactivity
Human, Rat
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Alternative names
MRT34; RAIDD antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human RAIDD
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000-1:2000
1:20-1:50
1:20
1:20
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Validations
Western blot detection of RAIDD in K562 cell lysates using RAIDD Rabbit mAb(1:1000 diluted).Predicted band size:23kDa.Observed band size:23kDa.
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Background
Swiss-Prot Acc.P78560.Adapter protein that associates with PIDD1 and the caspase CASP2 to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis (PubMed:9044836, PubMed:15073321, PubMed:16652156, PubMed:17159900, PubMed:17289572). Also recruits CASP2 to the TNFR-1 signaling complex through its interaction with RIPK1 and TRADD and may play a role in the tumor necrosis factor-mediated signaling pathway (PubMed:8985253).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"