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Product Name
Human CEP72 Recombinant protein (His tag)
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Description
Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) (PubMed:19536135). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:26297806). {PubMed:19536135, PubMed:26297806}.
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Protein name
Centrosomal protein of 72 kDa
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Protein short names
KIAA1519
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Uniprot ID
Q9P209
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Gene Name
CEP72; KIAA1519
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human CEP72 (NP_060610.2) 300-647 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human CEP72 SDS-PAGE
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