Human CDK7/CAK/CAK1/CDKN7/MO15/STK1 (His tag) recombinant protein

Cat.#: 518697

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Product Information

  • Product Name
    Human CDK7/CAK/CAK1/CDKN7/MO15/STK1 (His tag) recombinant protein
  • Documents
  • Description
    Cyclin-dependent kinase 7 (CDK7) belongs to the CMGC Ser/Thr superfamily, CDK7 colocalizes with PRKCI in the cytoplasm and nucleus, translocating from the nucleus to cytoplasm and perinuclear region in response to DNA-bound peptides. As a serine/threonine kinase CDK7 is involved in cell cycle control and RNA polymerase II-mediated RNA transcription. In addition, CDK7 is the catalytic subunit of the CDK-activating kinase complex, which phosphorylates SPT5/SUPT5H, SF1/NR5A1, POLR2A, p53/TP53, CDK1, CDK2, CDK4, CDK6 and CDK11B/CDK11.
  • Protein name
    cyclin dependent kinase 7(CDK7)
  • Protein short names
    CAK; CAK1; CDKN7; MO15; STK1
  • Uniprot ID
    P50613
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human CDK7/CAK/CAK1/CDKN7/MO15/STK1 Met1-Phe346 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human CDK7/CAK/CAK1/CDKN7/MO15/STK1 (His tag) recombinant protein

    Human CDK7/CAK/CAK1/CDKN7/MO15/STK1 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"