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Human CD41/Integrin alpha 2b Recombinant protein (GST tag)

Cat.#: 506407

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Special Price 294.7 USD

Availability: 2-3 weeks
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Product Information

  • Product Name
    Human CD41/Integrin alpha 2b Recombinant protein (GST tag)
  • Documents
  • Description
    Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
  • Protein name
    Integrin alpha-IIb
  • Protein short names
    GP2B; ITGAB
  • Uniprot ID
    P08514
  • Gene Name
    ITGA2B; GP2B; ITGAB
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human ITGA2B (XP_011523051.2) 729-945 aa was fused with the N-terminal GST tag
  • Protein Species
    Human
  • Activity
    Not tested.
  • Validations

    Recombinant human CD41/Integrin alpha 2b SDS-PAGE

    Recombinant human CD41/Integrin alpha 2b SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"