Human CD200R1/CD200R/CRTR2 (Fc tag) recombinant protein

Cat.#: 519104

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Product Information

  • Product Name
    Human CD200R1/CD200R/CRTR2 (Fc tag) recombinant protein
  • Documents
  • Description
    Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.
  • Protein name
    CD200 receptor 1(CD200R1)
  • Protein short names
    CD200R; CRTR2; MOX2R; OX2R; UNQ2522; PRO6015
  • Uniprot ID
    Q8TD46
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human CD200R1/CD200R/CRTR2 Ala27-Leu266 is expressed with a Fc tag at the C-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human CD200R1/CD200R/CRTR2 (Fc tag) recombinant protein

    Human CD200R1/CD200R/CRTR2 (Fc tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"