Human CBS Recombinant protein (His tag)

Human CBS Recombinant protein (His tag)

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Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (PubMed:23981774, PubMed:20506325, PubMed:23974653). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity). {UniProtKB:P32232, PubMed:20506325, PubMed:23974653, PubMed:23981774}.

Cystathionine beta-synthase

P35520

CBS

E. coli

A DNA sequence encoding the human CBS (XP_047296975.1) 223-568 aa was fused with the polyhistidine tag

Human

Not tested.