Human BPIFB1 / LPLUNC1 (His Tag) recombinant protein

Cat.#: 503187

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Product Information

  • Product Name
    Human BPIFB1 / LPLUNC1 (His Tag) recombinant protein
  • Documents
  • Description
    BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cells within the diseased epithelium, plays a role in the pathogenesis of the disease. BPIFB1 is an abundant, secreted product of goblet cells and minor mucosal glands of the respiratory tract and oral cavity and suggest that the protein functions in the complex milieu that protects the mucosal surfaces in these locations.
  • Protein name
    BPI fold-containing family B member 1
  • Protein short names
    LONG PALATE; BPI FOLD CONTAINING FAMILY B; BPIFB1; LUNG AND NASAL EPITHELIUM CARCINOMA-ASSOCIATED PROTEIN 1; C20ORF114; LPLUNC1; RP23-154J12.1; BPI FOLD-CONTAINING FAMILY B MEMBER 1; LUNG AND NASAL EPITHELIUM CARCINOMA ASSOCIATED 1; LONG PALATE; MEMBER 1; VON EBNER MINOR SALIVARY PROTEIN; VON EBNER MINOR SALIVARY GLAND PROTEIN
  • Uniprot ID
    Q8TDL5
  • Gene Name
    BPIFB1; C20orf114; LPLUNC1; UNQ706/PRO1357
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human BPIFB1 (AAH08429.1) (Met1-Gln484) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human BPIFB1 consists of 474 amino acids and predicts a molecular mass of 51.7 KDa. It migrates as an approximately 53 KDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human BPIFB1 / LPLUNC1 Protein (His Tag) SDS-PAGE

    Human BPIFB1 / LPLUNC1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"