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Product Name
Anti-BPIFB1 / LPLUNC1 antibody
- Documents
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Description
Rabbit polyclonal to BPIFB1 / LPLUNC1
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Tested applications
ELISA, IHC-P
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Species reactivity
Human BPIFB1 / LPLUNC1
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Alternative names
BPI fold containing family B antibody; member 1 antibody; Bpifb1 antibody; RP23-154J12.1 antibody; Lplunc1 antibody; BPI fold-containing family B member 1 antibody; long palate antibody; lung and nasal epithelium carcinoma associated 1 antibody; long palate antibody; lung and nasal epithelium carcinoma-associated protein 1 antibody; von Ebner minor salivary gland protein antibody; von Ebner minor salivary protein antibody; LPLUNC1 antibody; C20orf114 antibody; Lplunc1 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
Produced in rabbits immunized with purified, recombinant Human BPIFB1 / LPLUNC1 (rh BPIFB1 / LPLUNC1; AAH08429.1; Met1-Gln484). BPIFB1 / LPLUNC1 specific IgG was purified by Human BPIFB1 / LPLUNC1 affinity chromatography.
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Clonality
Polyclonal
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Formulation
0.2 μm filtered solution in PBS
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Storage instructions
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. -
Applications
ELISA:0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human BPIFB1 / LPLUNC1. The detection limit for Human BPIFB1 / LPLUNC1 is < 0.039 ng/well.
IHC-P: 0.1-1 μg/ml
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Validations
BPIFB1 / LPLUNC1 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry
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Background
BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cells within the diseased epithelium, plays a role in the pathogenesis of the disease. BPIFB1 is an abundant, secreted product of goblet cells and minor mucosal glands of the respiratory tract and oral cavity and suggest that the protein functions in the complex milieu that protects the mucosal surfaces in these locations.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"