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Product Name
Human TALLA-1 / TSPAN7 (CD231) (His Tag) recombinant protein
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Description
BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cells within the diseased epithelium, plays a role in the pathogenesis of the disease. BPIFB1 is an abundant, secreted product of goblet cells and minor mucosal glands of the respiratory tract and oral cavity and suggest that the protein functions in the complex milieu that protects the mucosal surfaces in these locations.
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Protein name
BPI fold-containing family B member 1
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Protein short names
LONG PALATE; BPI FOLD CONTAINING FAMILY B; BPIFB1; LUNG AND NASAL EPITHELIUM CARCINOMA-ASSOCIATED PROTEIN 1; C20ORF114; LPLUNC1; RP23-154J12.1; BPI FOLD-CONTAINING FAMILY B MEMBER 1; LUNG AND NASAL EPITHELIUM CARCINOMA ASSOCIATED 1; LONG PALATE; MEMBER 1; VON EBNER MINOR SALIVARY PROTEIN; VON EBNER MINOR SALIVARY GLAND PROTEIN
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Uniprot ID
Q8TDL5
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Gene Name
BPIFB1; C20orf114; LPLUNC1; UNQ706/PRO1357
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human TSPAN7 (AAH08429.1) (Arg113-Met213) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human TSPAN7 consists of 112 amino acids and predicts a molecular mass of 13 KDa. It migrates as an approximately 24-30 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human TALLA-1 / TSPAN7 Protein (His Tag) SDS-PAGE
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