-
Product Name
Human BGN/SLRR1A (His tag) recombinant protein
- Documents
-
Description
Biglycan is a 200-350 kD proteoglycan consisting of a 45 kD core protein and two chrondroitin/dermatan sulfate glycosaminoglycan chains. Biglycan binds to TGF-ß. It also binds to collagen type I in low ionic strength (less than 3 mM phosphate) buffer. At higher ionic strengths, Biglycan does not bind to collagen type I. It enhances the inhibition effect of TGF-ß on osteoclast proliferation at a concentration of 4-20 mg/ml. It also prevents the attachment of CHO cells to fibronectin, with a 50% inhibition at 17-21 mg/ml.
-
Protein name
biglycan(BGN)
-
Protein short names
SLRR1A
-
Uniprot ID
P21810
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human BGN/SLRR1A Glu20-Lys368 is expressed with a 6His tag at the C-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human BGN/SLRR1A (His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"