Anti-BGN antibody

Anti-BGN antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit Polyclonal to Human BGN

IHC-P

Human Biglycan

Biglycan antibody; BGN antibody; DSPG1 antibody; PG-S1 antibody; PGI antibody; SLRR1A antibody; biglycan proteoglycan antibody; bone/cartilage proteoglycan I antibody; dermatan sulphate proteoglycan I antibody; small antibody; Biglycan antibody; Bgn antibody; RP23-95K12.7 antibody; BG antibody; DSPG1 antibody; PG-S1 antibody; PGI antibody; SLRR1A antibody; bone/cartilage proteoglycan I antibody; PGI antibody; DSPG1 antibody; PG-S1 antibody; SLRR1A antibody; BG antibody; PGI antibody; DSPG1 antibody; PG-S1 antibody; SLRR1A antibody

Rabbit IgG

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human Biglycan, and purified by antigen affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Biglycan, also known as PG-S1 and BGN, is a a small leucine-rich repeat proteoglycan (SLRP). It can be detected in a variety of extracellular matrix tissues, including bone, cartilage and tendon. Biglycan consists of a protein core containing leucine-rich repeat regions and two glycosaminoglycan (GAG) chains consisting of either chondroitin sulfate (CS) or dermatan sulfate (DS). Non-glycanated forms of biglycan (no GAG chains) increase with age in human articular cartilage. Biglycan interacts with collagen, both via the core protein and GAG chains. Biglycan plays a role in the mineralisation of bone. Biglycan core protein binds to the growth factors BMP-4 and influences its bioactivity.