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Product Name
Human BDNF recombinant protein
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Description
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
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Protein name
brain derived neurotrophic factor(BDNF)
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Uniprot ID
P23560
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human BDNF His129-Arg247 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human BDNF recombinant protein
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