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Product Name
Mouse BDNF recombinant protein
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Description
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
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Protein name
Brain-derived neurotrophic factor
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Protein short names
ANON2; BULN2; MGC34632; RP23-393E8.1; ABRINEURIN; ANOREXIA BDNF; BRAIN-DERIVED NEUROTROPHIC FACTOR; NEUROTROPHIN
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Uniprot ID
P21237
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Gene Name
Bdnf
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Source/Expression Host
CHO Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse BDNF (P21237) (Met1-Arg249) was expressed and its mature form was purified. The mature form of human, mouse, rat, cynomolgus and canine BDNF sequences are identical.
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Protein Species
Mouse
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Molecular weight
The recombinant mature form of mouse BDNF consists of 119 amino acids and predicts a molecular mass of 13.5 KDa.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
1. Measured by its ability to bind biotinylated human TrkB-His (Cat:500790) in functional ELISA.
2. Measured by its ability to bind Human TrkB-Fch (Cat:503265) in functional ELISA.
3. Measured by its ability to bind biotinylated mouse TrkB-His (Cat:501573) in functional ELISA. -
Validations
Mouse / Human BDNF Protein SDS-PAGE
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