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Product Name
Human ATG10/APG10L/PP12616 (His tag) recombinant protein
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Description
Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or ATG7.
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Protein name
autophagy related 10(ATG10)
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Protein short names
APG10L; PP12616
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Uniprot ID
Q9H0Y0
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ATG10/APG10L/PP12616 Met1-Thr190 is expressed with a T7 tag at the N-terminus, 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ATG10/APG10L/PP12616 (His tag) recombinant protein
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