Human AP3B2 Recombinant protein (His tag)

Human AP3B2 Recombinant protein (His tag)

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Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

AP-3 complex subunit beta-2

Q13367

AP3B2

E. coli

A DNA sequence encoding the human AP3B2 (NP_004635.2) 650-1082 aa was fused with the polyhistidine tag

Human

Not tested.