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Product Name
AP3B2 antibody
- Documents
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Description
AP3B2 Rabbit Polyclonal antibody. Positive WB detected in rat brain tissue, mouse brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 120-140 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
AP 3 complex subunit beta 2 antibody; AP3B2 antibody; Beta 3B adaptin antibody; DKFZp686D17136 antibody; NAPTB antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of AP3B2 recombinant protein (Accession Number: NM_004644). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
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Validations
rat brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:108122(AP3B2 Antibody) at dilution of 1:600
IP Result of anti-AP3B2 (IP:Catalog No:108122, 4ug; Detection:Catalog No:108122 1:500) with mouse brain tissue lysate 3600ug.
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Background
Adaptor protein (AP) complexes are cytosolic heterotetramers that mediate the sorting of membrane proteins in the secretory and endocytic pathways. AP3B2 is a subunit of the AP-3 complex which is composed of two large adaptins (AP3D1 and AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP-3 complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
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