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Product Name
Human ANG/RNASE5 recombinant protein
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Description
Angiogenin belongs to the pancreatic ribonuclease family. Angiogenin is primarily expressed in the liver. It may act as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Angiogenin is a potent stimulator of new blood vessel formation. And Angiogenin is endocytosed and translocated to the nucleus by binding to actin on the surface of endothelial cells. Angiogenic activity is regulated by interaction with RNH1 in vivo. In addition, Angiogenin is associated with susceptibility to amyotrophic lateral sclerosis, which is a degenerative disorder of motor neurons in the cortex, brain stem and spinal cord.
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Protein name
angiogenin(ANG)
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Protein short names
RNASE5
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Uniprot ID
P03950
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ANG/RNASE5 Gln25-Pro147 is expressed.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ANG/RNASE5 recombinant protein
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