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Product Name
Human HBP1 (GST Tag) recombinant protein
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Description
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
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Protein name
HMG box-containing protein 1
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Protein short names
BE629963; HBP1; HMG BOX TRANSCRIPTION FACTOR 1; C86454; HMG BOX-CONTAINING PROTEIN 1; C330012F01RIK; 1700058O05RIK; HIGH MOBILITY GROUP BOX TRANSCRIPTION FACTOR 1
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Uniprot ID
O60381
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Gene Name
HBP1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human HBP1 (O60381-1) (Pro208-Phe345) was fused with the GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human HBP1 /GST chimera consists of 372 amino acids and has a predicted molecular mass of 42.5 kDa. It migrates as an approximately 43 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human HBP1 Protein (GST Tag) SDS-PAGE
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