Histone H4 Polyclonal Antibody

Cat.#: 163401

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Product Information

  • Product Name
    Histone H4 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to Histone H4
  • Tested applications
    IHC, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    HIST1H4B antibody; H4/I antibody; H4FI antibody; histone H4 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Histone H4.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    IHC 1:50 - 1:200
    IF 1:50 - 1:200
  • Validations

    Immunofluorescence - Histone H4 Polyclonal Antibody

    Immunofluorescence - Histone H4 Polyclonal Antibody

    Immunofluorescence analysis of C6 cells using Histone H4 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

    Immunofluorescence - Histone H4 Polyclonal Antibody

    Immunofluorescence - Histone H4 Polyclonal Antibody

    Immunofluorescence analysis of HeLa cells using Histone H4 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

    Immunofluorescence - Histone H4 Polyclonal Antibody

    Immunofluorescence - Histone H4 Polyclonal Antibody

    Immunofluorescence analysis of NIH/3T3 cells using Histone H4 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

  • Background
    Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"