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Product Name
Human HIST2H4A recombinant protein
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Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
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Protein name
Histone H4
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Protein short names
HIST2H4; H4FN; FO108; H4/N; H4; H4F2
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Uniprot ID
P62805
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Gene Name
HIST1H4H; HIST1H4J; HIST1H4L; hCG_1640981
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human Histone H4 (NP_003539.1) (Met1-Gly103) was expressed.
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Protein Species
Human
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Molecular weight
The recombinant human Histone H4 consists of 103 amino acids and predicts a molecular mass of 11.4 kDa. It migrates as an approximately 12 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human Histone H4 / HIST2H4A Protein SDS-PAGE
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