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Product Name
Anti-Histone H4 Rabbit antibody
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Description
Histone H4 Rabbit monoclonal antibody
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Tested applications
WB, IHC-P, ICC/IF, ChIP
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Species reactivity
Human, Mouse, Rat
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Alternative names
H4/p antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human Histone H4
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Clonality
Monoclonal
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Formulation
Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Storage instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze / thaw cycle.
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Applications
1:1000
1:200
1:20
1:20
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Validations
Western blot detection of Histone H4 in Hela cell lysates using Histone H4 Rabbit mAb(1:1000 diluted).Predicted band size:11kDa.Observed band size:11kDa.
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Background
Swiss-Prot Acc.P62805.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.RegionsFeature keyPosition(s)Description
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"