-
Product Name
Human HIST2H2BE recombinant protein
- Documents
-
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
-
Protein name
Histone H2B type 2-E
-
Protein short names
T25626; MGC119802; MGC129734; H2BGL105; H2BFQ; MGC119804; H2B-613; MGC129733; GL105; H2B.1; H2B; H2BQ; AV127319
-
Uniprot ID
Q16778
-
Gene Name
HIST2H2BE; H2BFQ
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the human HIST2H2BE (Q16778) (Met 1-Lys 126) was expressed and purified.
-
Protein Species
Human
-
Molecular weight
The recombinant human HIST2H2BE consists of 126 amino acids and has a calculated molecular mass of 14.2 kDa. It migrates as an 16 kDa band in SDS-PAGE under reducing conditions.
-
Purity
> 95 % as determined by SDS-PAGE
-
Validations
Human Histone cluster 2 H2BE / HIST2H2BE Protein SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"