HAT1 Polyclonal Antibody

Cat.#: 163744

Special Price 290.3 USD

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Product Information

  • Product Name
    HAT1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to HAT1
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    HAT1 antibody; KAT1 antibody; histone acetyltransferase 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human HAT1
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, pH7.3.
  • Storage instructions
    Store at 4℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:1000
  • Validations

    Western blot - HAT1 Polyclonal Antibody

    Western blot - HAT1 Polyclonal Antibody

    Western blot analysis of extracts of Jurkat cells, using HAT1 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

  • Background
    Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"