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Product Name
Human USH1C/Harmonin (His Tag) recombinant protein
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Description
Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing (By similarity).
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Protein name
Harmonin
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Protein short names
USH1C; PDZD7C; AIE-75; PDZ-45; NY-CO-37; PDZ73; USH1CPST; 2010016F01RIK; DFNB18; PDZ-73/NY-CO-38; HARMONIN; DFNB18A; NY-CO-38; PDZ-73
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Uniprot ID
Q9Y6N9
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Gene Name
USH1C; AIE75
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the native human USH1C (Q9Y6N9-1) (Met 1-Phe 552) was expressed, with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human USH1C consisting of 563 amino acids and migrates as an 63.7 kDa band in SDS-PAGE under reducing conditions as predicted.
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Purity
> 92 % as determined by SDS-PAGE
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Validations
Human USH1C / Harmonin Protein (His Tag) SDS-PAGE
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