Anti-USH1C/Harmonin antibody

Anti-USH1C/Harmonin antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Rabbit polyclonal to USH1C/Harmonin

ELISA, WB, IHC-P, IP

Human USH1C / Harmonin

PDZ73 antibody; AIE-75 antibody; DFNB18 antibody; PDZ-45 antibody; PDZ-73 antibody; PDZD7C antibody; DFNB18A antibody; NY-CO-37 antibody; NY-CO-38 antibody; ush1cpst antibody; PDZ-73/NY-CO-38 antibody; harmonin antibody; 2010016F01Rik antibody; 2010016F01Rik antibody; AIE-75 antibody; DFNB18 antibody; harmonin antibody; Harmonin antibody; NY-CO-37 antibody; NY-CO-38 antibody; PDZ-45 antibody; PDZ73 antibody; PDZ-73 antibody; PDZ-73/NY-CO-38 antibody; Ush1c antibody; USH1C antibody; ush1cpst antibody

Rabbit IgG

Produced in rabbits immunized with purified, recombinant Human USH1C / Harmonin (rh USH1C / Harmonin; Q9Y6N9-1; Met 1-Phe 552). USH1C / Harmonin specific IgG was purified by Human USH1C / Harmonin affinity chromatography.

Polyclonal

0.2 μm filtered solution in PBS with 5% trehalose

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Harmonin, also known as Antigen NY-CO-38 / NY-CO-37, Autoimmune enteropathy-related antigen AIE-75, Protein PDZ-73, Renal carcinoma antigen NY-REN-3, Usher syndrome type-1C protein and USH1C, is a protein which is expressed in small intestine, colon, kidney, eye and weakly in pancreas. USH1C is expressed also in vestibule of the inner ear. USH1C contains 3 PDZ (DHR) domains. USH1C may be involved in protein-protein interaction. Defects in USH1C are the cause of Usher syndrome type 1C (USH1C), also known as Usher syndrome type I Acadian variety. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa and sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). Defects in USH1C are also the cause of deafness autosomal recessive type 18 (DFNB18) which is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.

• Verpy, E. et al., 2000, Nat Genet. 26 (1):51-5.
• Weil D., et al., 2003, Hum. Mol. Genet. 12:463-471.
• Reiners,J. et al., 2005, Hum Mol Genet. 14 (24):3933-43.
• Yan,D. et al., 2006, Mol Biol. 357 (3):755-64.