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Product Name
GRB14 antibody
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Description
GRB14 Rabbit Polyclonal antibody. Positive IHC detected in human ovary tumor tissue. Positive WB detected in DU 145 cells. Observed molecular weight by Western-blot: 61kd
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GRB14 antibody; GRB14 adapter protein antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GRB14 recombinant protein (Accession Number: NM_004490). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:111199(GRB14 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:111199(GRB14 antibody) at dilution of 1:50 (under 40x lens)
DU 145 cells were subjected to SDS PAGE followed by western blot with Catalog No:111199(GRB14 Antibody) at dilution of 1:600
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Background
GRB14 belongs to the GRB7/10/14 family. It is an adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. GRB14 is a target for a PDGF regulated serine kinase, an interaction that does not require PDGFR-GRB14 association. GRB14 is about 58-65kd in WB test.
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