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Product Name
GM2A antibody
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Description
GM2A Mouse Monoclonal antibody. Positive WB detected in Hela cells, human placenta tissue. Observed molecular weight by Western-blot: 22 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
Ganglioside GM2 activator antibody; GM2 AP antibody; GM2 ganglioside activator antibody; GM2A antibody; SAP 3 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of GM2A recombinant protein (Accession Number: NM_000405). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107302(GM2A antibody) at dilution of 1:500
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Background
GM2A, also named as GM2-AP and SAP-3, is the large binding pocket which can accommodate several single chain phospholipids and fatty acids. GM2A also exhibits some calcium-independent phospholipase activity. It plays a key role in the degradation of ganglioside GM2 (GM2). GM2A stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"