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Product Name
GCDFP-15/PIP antibody
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Description
GCDFP-15/PIP Rabbit Polyclonal antibody. Positive IHC detected in human skin tissue, human breast cancer tissue, human breast tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
GCDFP 15 antibody; GCDFP15 antibody; gp17 antibody; GPIP4 antibody; PIP antibody; prolactin induced protein antibody; Prolactin inducible protein antibody; SABP antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GCDFP-15/PIP recombinant protein (Accession Number: NM_002652). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human skin using Catalog No:110900(GCDFP-15, PIP antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemical of paraffin-embedded human skin using Catalog No:110900(GCDFP-15, PIP antibody) at dilution of 1:50 (under 10x lens)
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Background
GCDFP-15 (gross cystic disease fluid protein 15), also known as PIP (prolactin-induced protein) is a secretory glycoprotein expressed in benign and malignant breast tumor tissues and in some normal exocrine organs such as sweat, salivary, and lacrimal glands (PMID: 12393800). GCDFP-15 expression is increased by prolactin and androgen and inhibited by estrogen (PMID: 18854942). The expression is also regulated by interleukins. GCDFP-15 is a marker of apocrine differentiation and is frequently used for assessment of metastases or regional recurrences of breast origin.
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