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Product Name
Gastrokine 1 antibody
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Description
Gastrokine 1 Rabbit Polyclonal antibody. Positive IHC detected in human stomach tissue. Positive WB detected in human stomach tissue, mouse stomach tissue. Observed molecular weight by Western-blot: 20-22 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
18 kDa antrum mucosa protein antibody; AMP 18 antibody; AMP18 antibody; BRICD1 antibody; CA11 antibody; FOV antibody; foveolin antibody; gastrokine 1 antibody; GKN1 antibody; Protein CA11 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Gastrokine 1 recombinant protein (Accession Number: BC059778). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IHC: 1:20-1:200
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Validations
human stomach tissue were subjected to SDS PAGE followed by western blot with Catalog No:110877(GKN1 antibody) at dilution of 1:2000
Immunohistochemical of paraffin-embedded human stomach using Catalog No:110877(GKN1 antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human stomach using Catalog No:110877(GKN1 antibody) at dilution of 1:100 (under 40x lens)
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Background
Gastrokine 1 (GKN1), a stomach-specific protein also known as 18 kDa antrum mucosa protein (AMP-18) or foveolin, belongs to the gastrokine family of gastric mucus cell-secreted proteins. The human GKN1 gene has been localized in a region of chromosome 2p13 of about 6 kb and contains 6 exons. GKN1 is expressed only in normal human stomach, but is absent from gastric adenocarcinomas, gastro-esophageal adenocarcinoma cell lines, and other normal and tumor gastro-intestinal tissues. GKN1may play an important role in normal gastric function and may be a gastric tumour suppressor.
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