Galectin-3 antibody

Galectin-3 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

Galectin-3 Mouse Monoclonal antibody. Positive WB detected in Hela cells. Positive IHC detected in human thyroid cancer tissue, human colon tissue. Positive IF detected in MCF-7 cells. Observed molecular weight by Western-blot: 31 kDa

ELISA, WB, IF, IHC

Human,Mouse; other species not tested.

35 kDa lectin antibody; CBP 35 antibody; CBP35 antibody; Gal 3 antibody; GAL3 antibody; Galactose specific lectin 3 antibody; Galactoside binding protein antibody; GALBP antibody; Galectin 3 antibody; Galectin-3 antibody; GALIG antibody; IgE binding protein antibody; L 31 antibody; Laminin binding protein antibody; Lectin L 29 antibody; LGALS2 antibody; LGALS3 antibody; Mac 2 antigen antibody; MAC2 antibody

Mouse IgG2b

This antibody was obtained by immunization of Galectin-3 recombinant protein (Accession Number: NM_002306). Purification method: Protein A purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for β-galactose-containing oligosac-charides (PMID: 8063692). Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell, being present on the cell surface or in the extracellular space (PMID: 16478649). Galectin-3 is involved in various biological processes including cell growth, adhesion, differentiation, apoptosis, angiogenesis, immune response, neoplastic transformation and metastasis (PMID: 16478649; 14758078).

• Yang Z, Zheng B, Zhang Y. miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells. Biochimica et biophysica acta. 1852(7):1477-89. 2015.