FKBP8 Polyclonal Antibody

Cat.#: 161209

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Product Information

  • Product Name
    FKBP8 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to FKBP8
  • Tested applications
    WB, IF, IP
  • Species reactivity
    Human, Mouse
  • Alternative names
    FKBP8 antibody; FKBP38 antibody; FKBPr38 antibody; FK506 binding protein 8 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant protein of human FKBP8
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:20 - 1:100
    IP 1:20 - 1:50
  • Validations

    Western blot - FKBP8 Polyclonal Antibody

    Western blot - FKBP8 Polyclonal Antibody

    Western blot analysis of extracts of Jurkat cells, using FKBP8 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

  • Background
    Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"